6J8J

Structure of human voltage-gated sodium channel Nav1.7 in complex with auxiliary beta subunits, ProTx-II and tetrodotoxin (Y1755 down)

Summary for 6J8J

• Entry DOI: 10.2210/pdb6j8j/pdb
• EMDB information: 9782
• Descriptor: Sodium channel subunit beta-2, Sodium channel protein type 9 subunit alpha, Sodium channel subunit beta-1, ... (6 entities in total)
• Functional Keywords: voltage-gated sodium channel, membrane protein
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 3
• Total formula weight: 283016.42

Authors

Shen, H.,Liu, D.,Lei, J.,Yan, N. (deposition date: 2019-01-19, release date: 2019-02-27, Last modification date: 2020-07-29)

• Primary citation: Shen, H.,Liu, D.,Wu, K.,Lei, J.,Yan, N.; Structures of human Nav1.7 channel in complex with auxiliary subunits and animal toxins.; Science, 363:1303-1308, 2019; PubMed: 30765606; DOI: 10.1126/science.aaw2493

Experimental method

ELECTRON MICROSCOPY (3.2 Å)