6J5D

Complex structure of MAb 4.2-scFv with louping ill virus envelope protein Domain III

Summary for 6J5D

DescriptorEnvelope, antibody heavy chain, antibody light chain, ... (4 entities in total)
Functional Keywordsprotective and neutralizing antibody, flavivirus envelope protein, antiviral protein, viral protein-immune system complex, viral protein/immune system
Biological sourceLouping ill virus (Li)
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Total number of polymer chains3
Total molecular weight36124.22
Authors
Yang, X.,Qi, J.,Peng, R.,Dai, L.,Gould, E.A.,Tien, P.,Gao, G.F. (deposition date: 2019-01-10, release date: 2019-02-06)
Primary citation
Yang, X.,Qi, J.,Peng, R.,Dai, L.,Gould, E.A.,Gao, G.F.,Tien, P.
Molecular basis of a protective/neutralizing monoclonal antibody targeting envelope proteins of both tick-borne encephalitis virus and louping ill virus
To Be Published,
Experimental method
X-RAY DIFFRACTION (1.8 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.18940 0.7% 2.5%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

Molmil generated image of 6j5d
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Molmil generated image of 6j5d
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Molmil generated image of 6j5d
rotated about y axis by 90°
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