6J4P

Structural basis of tubulin detyrosination by vasohibins-SVBP enzyme complex and functional implications

6J4P の概要

• エントリーDOI: 10.2210/pdb6j4p/pdb
• 分子名称: Tubulinyl-Tyr carboxypeptidase 2, Small vasohibin-binding protein, N-[(3R)-4-ethoxy-3-hydroxy-4-oxobutanoyl]-L-tyrosine, ... (4 entities in total)
• 機能のキーワード: carboxypeptidase, tubulin, microtubule, inhibitor, epoy, hydrolase
• 由来する生物種: Homo sapiens (Human); 詳細
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 37469.67

構造登録者

Wang, N.,Bao, H.,Huang, H. (登録日: 2019-01-10, 公開日: 2019-05-01, 最終更新日: 2023-11-22)

• 主引用文献: Wang, N.,Bosc, C.,Ryul Choi, S.,Boulan, B.,Peris, L.,Olieric, N.,Bao, H.,Krichen, F.,Chen, L.,Andrieux, A.,Olieric, V.,Moutin, M.J.,Steinmetz, M.O.,Huang, H.; Structural basis of tubulin detyrosination by the vasohibin-SVBP enzyme complex.; Nat.Struct.Mol.Biol., 26:571-582, 2019; PubMed: 31235911; DOI: 10.1038/s41594-019-0241-y

実験手法

X-RAY DIFFRACTION (1.599 Å)