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6IZX

The RNA-dependent RNA polymerase domain of dengue 2 NS5, bound with RK-0404678

Summary for 6IZX
Entry DOI10.2210/pdb6izx/pdb
DescriptorGenome polyprotein, ZINC ION, COBALT (II) ION, ... (5 entities in total)
Functional Keywordsdengue, ns5, rna-dependent rna polymerase, viral protein
Biological sourceDengue virus 2
Total number of polymer chains1
Total formula weight80708.68
Authors
Shimizu, H.,Sekine, S. (deposition date: 2018-12-20, release date: 2019-12-25, Last modification date: 2023-11-22)
Primary citationShimizu, H.,Saito, A.,Mikuni, J.,Nakayama, E.E.,Koyama, H.,Honma, T.,Shirouzu, M.,Sekine, S.I.,Shioda, T.
Discovery of a small molecule inhibitor targeting dengue virus NS5 RNA-dependent RNA polymerase.
Plos Negl Trop Dis, 13:e0007894-e0007894, 2019
Cited by
PubMed: 31738758
DOI: 10.1371/journal.pntd.0007894
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.43 Å)
Structure validation

217705

数据于2024-03-27公开中

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