6IW7
structural insights into Mycobacterium tuberculosis ClpP1P2 inhibition by Cediranib: implications for developing antimicrobial agents targeting Clp protease
Summary for 6IW7
Entry DOI | 10.2210/pdb6iw7/pdb |
Related PRD ID | PRD_002200 |
Descriptor | ATP-dependent Clp protease proteolytic subunit 2, ATP-dependent Clp protease proteolytic subunit 1, (2S)-2-benzamido-4-methyl-pentanoic acid, ... (6 entities in total) |
Functional Keywords | mycobacterium tuberculosis, antimicrobial agents, clpp1p2, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
Biological source | Mycobacterium tuberculosis CDC1551 More |
Total number of polymer chains | 14 |
Total formula weight | 311392.70 |
Authors | Bao, R.,Luo, Y.F.,Zhu, Y.B.,Yang, Y.,Zhou, Y.Z. (deposition date: 2018-12-04, release date: 2020-01-01, Last modification date: 2023-11-29) |
Primary citation | Bao, R.,Luo, Y.F.,Zhu, Y.B.,Yang, Y.,Yang, T. structural insights into Mycobacterium tuberculosis ClpP1P2 inhibition by Cediranib: implications for developing antimicrobial agents targeting Clp protease To Be Published, |
Experimental method | X-RAY DIFFRACTION (2.69212103413 Å) |
Structure validation
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