6IW7

structural insights into Mycobacterium tuberculosis ClpP1P2 inhibition by Cediranib: implications for developing antimicrobial agents targeting Clp protease

Summary for 6IW7

• Entry DOI: 10.2210/pdb6iw7/pdb
• Related PRD ID: PRD_002200
• Descriptor: ATP-dependent Clp protease proteolytic subunit 2, ATP-dependent Clp protease proteolytic subunit 1, (2S)-2-benzamido-4-methyl-pentanoic acid, ... (6 entities in total)
• Functional Keywords: mycobacterium tuberculosis, antimicrobial agents, clpp1p2, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
• Biological source: Mycobacterium tuberculosis CDC1551; More
• Total number of polymer chains: 14
• Total formula weight: 311392.70

Authors

Bao, R.,Luo, Y.F.,Zhu, Y.B.,Yang, Y.,Zhou, Y.Z. (deposition date: 2018-12-04, release date: 2020-01-01, Last modification date: 2023-11-29)

• Primary citation: Bao, R.,Luo, Y.F.,Zhu, Y.B.,Yang, Y.,Yang, T.; structural insights into Mycobacterium tuberculosis ClpP1P2 inhibition by Cediranib: implications for developing antimicrobial agents targeting Clp protease; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.69212103413 Å)