6IW7

structural insights into Mycobacterium tuberculosis ClpP1P2 inhibition by Cediranib: implications for developing antimicrobial agents targeting Clp protease

6IW7 の概要

• エントリーDOI: 10.2210/pdb6iw7/pdb
• 関連するBIRD辞書のPRD_ID: PRD_002200
• 分子名称: ATP-dependent Clp protease proteolytic subunit 2, ATP-dependent Clp protease proteolytic subunit 1, (2S)-2-benzamido-4-methyl-pentanoic acid, ... (6 entities in total)
• 機能のキーワード: hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
• 由来する生物種: Mycobacterium tuberculosis CDC1551; 詳細
• タンパク質・核酸の鎖数: 14
• 化学式量合計: 311392.70

構造登録者

Bao, R.,Luo, Y.F.,Zhu, Y.B.,Yang, Y.,Zhou, Y.Z. (登録日: 2018-12-04, 公開日: 2020-01-01, 最終更新日: 2024-11-06)

• 主引用文献: Bao, R.,Luo, Y.F.,Zhu, Y.B.,Yang, Y.,Yang, T.; structural insights into Mycobacterium tuberculosis ClpP1P2 inhibition by Cediranib: implications for developing antimicrobial agents targeting Clp protease; To Be Published,

実験手法

X-RAY DIFFRACTION (2.69212103413 Å)