Crystal structure of YFV-17D sE in postfusion state

Summary for 6IW1

DescriptorEnvelope protein E (1 entity in total)
Functional Keywordsyellow fever virus, envelope protein, flavivirus, viral protein
Biological sourceYellow fever virus (strain 17D vaccine) (YFV)
Total number of polymer chains3
Total molecular weight129704.54
Lu, X.S.,Xiao, H.X.,Li, S.H.,Pang, X.F. (deposition date: 2018-12-04, release date: 2019-02-13)
Primary citation
Lu, X.,Xiao, H.,Li, S.,Pang, X.,Song, J.,Liu, S.,Cheng, H.,Li, Y.,Wang, X.,Huang, C.,Guo, T.,Ter Meulen, J.,Daffis, S.,Yan, J.,Dai, L.,Rao, Z.,Klenk, H.D.,Qi, J.,Shi, Y.,Gao, G.F.
Double Lock of a Human Neutralizing and Protective Monoclonal Antibody Targeting the Yellow Fever Virus Envelope.
Cell Rep, 26:438-446.e5, 2019
PubMed: 30625326 (PDB entries with the same primary citation)
DOI: 10.1016/j.celrep.2018.12.065
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.25711 0.3% 13.0% 1.6%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

Molmil generated image of 6iw1
no rotation
Molmil generated image of 6iw1
rotated about x axis by 90°
Molmil generated image of 6iw1
rotated about y axis by 90°