6IRW

Crystal structure of the human cap-specific adenosine methyltransferase bound to SAH

6IRW の概要

• エントリーDOI: 10.2210/pdb6irw/pdb
• 分子名称: Phosphorylated CTD-interacting factor 1, S-ADENOSYL-L-HOMOCYSTEINE (3 entities in total)
• 機能のキーワード: rna methylation, methyltransferase, m6a, n6-methyladenosine, transferase
• 由来する生物種: Homo sapiens (Human)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 119554.88

構造登録者

Hirano, S.,Nishimasu, H.,Ishitani, R.,Nureki, O. (登録日: 2018-11-14, 公開日: 2018-12-05, 最終更新日: 2023-11-22)

• 主引用文献: Akichika, S.,Hirano, S.,Shichino, Y.,Suzuki, T.,Nishimasu, H.,Ishitani, R.,Sugita, A.,Hirose, Y.,Iwasaki, S.,Nureki, O.,Suzuki, T.; Cap-specific terminal N 6 -methylation of RNA by an RNA polymerase II-associated methyltransferase.; Science, 363:-, 2019; PubMed: 30467178; DOI: 10.1126/science.aav0080

実験手法

X-RAY DIFFRACTION (2.9 Å)