6IQH
X-ray crystal structure of covalent-bonded complex of Fc and peptide
This is a non-PDB format compatible entry.
Summary for 6IQH
Entry DOI | 10.2210/pdb6iqh/pdb |
Descriptor | Immunoglobulin gamma-1 heavy chain, 17-mer peptide (GPDCAYHKGELVWCTFH), 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose (3 entities in total) |
Functional Keywords | fc, complex, immune system |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 4 |
Total formula weight | 54631.01 |
Authors | Adachi, M.,Ito, Y. (deposition date: 2018-11-08, release date: 2019-02-13, Last modification date: 2024-01-24) |
Primary citation | Kishimoto, S.,Nakashimada, Y.,Yokota, R.,Hatanaka, T.,Adachi, M.,Ito, Y. Site-Specific Chemical Conjugation of Antibodies by Using Affinity Peptide for the Development of Therapeutic Antibody Format. Bioconjug. Chem., 30:698-702, 2019 Cited by PubMed: 30606013DOI: 10.1021/acs.bioconjchem.8b00865 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.999 Å) |
Structure validation
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