Crystal structure of a novel thermostable (S)-enantioselective omega-transaminase from Thermomicrobium roseum

Summary for 6IO1

DescriptorAminotransferase, class III, 4'-DEOXY-4'-AMINOPYRIDOXAL-5'-PHOSPHATE (3 entities in total)
Functional Keywordsenantioselectivity, omega-transaminase, substrate recognition thermomicrobium roseum, transamination, transferase
Biological sourceThermomicrobium roseum (strain ATCC 27502 / DSM 5159 / P-2)
Total number of polymer chains2
Total molecular weight99295.48
Park, H.H.,Kwon, S. (deposition date: 2018-10-29, release date: 2019-05-22)
Primary citation
Kwon, S.,Lee, J.H.,Kim, C.M.,Jang, H.,Yun, H.,Jeon, J.H.,So, I.,Park, H.H.
Structural basis of substrate recognition by a novel thermostable (S)-enantioselective omega-transaminase from Thermomicrobium roseum.
Sci Rep, 9:6958-6958, 2019
PubMed: 31061438 (PDB entries with the same primary citation)
DOI: 10.1038/s41598-019-43490-2
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.15250 0.3% 2.1%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution