6INE

Crystal Structure of human ASH1L-MRG15 complex

6INE の概要

• エントリーDOI: 10.2210/pdb6ine/pdb
• 分子名称: Histone-lysine N-methyltransferase ASH1L, Mortality factor 4-like protein 1, ZINC ION, ... (6 entities in total)
• 機能のキーワード: complex, h3k36 methyltransferase, transferase, transferase-protein binding complex, transferase/protein binding
• 由来する生物種: Homo sapiens (Human); 詳細
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 52353.84

構造登録者

Hou, P.,Huang, C.,Liu, C.P.,Yu, T.,Yin, Y.,Zhu, B.,Xu, R.M. (登録日: 2018-10-25, 公開日: 2019-03-20, 最終更新日: 2023-11-22)

• 主引用文献: Hou, P.,Huang, C.,Liu, C.P.,Yang, N.,Yu, T.,Yin, Y.,Zhu, B.,Xu, R.M.; Structural Insights into Stimulation of Ash1L's H3K36 Methyltransferase Activity through Mrg15 Binding.; Structure, 27:837-, 2019; PubMed: 30827843; DOI: 10.1016/j.str.2019.01.015

実験手法

X-RAY DIFFRACTION (2.6 Å)