6IIU
Crystal structure of the human thromboxane A2 receptor bound to ramatroban
Summary for 6IIU
Entry DOI | 10.2210/pdb6iiu/pdb |
Descriptor | Soluble cytochrome b562,Thromboxane A2 receptor,Rubredoxin,Thromboxane A2 receptor, 3-[(3R)-3-[(4-fluorophenyl)sulfonylamino]-1,2,3,4-tetrahydrocarbazol-9-yl]propanoic acid, ZINC ION, ... (7 entities in total) |
Functional Keywords | gpcr, complex, antagonist, signaling protein |
Biological source | Escherichia coli More |
Total number of polymer chains | 1 |
Total formula weight | 54915.94 |
Authors | |
Primary citation | Fan, H.,Chen, S.,Yuan, X.,Han, S.,Zhang, H.,Xia, W.,Xu, Y.,Zhao, Q.,Wu, B. Structural basis for ligand recognition of the human thromboxane A2receptor. Nat. Chem. Biol., 15:27-33, 2019 Cited by PubMed: 30510189DOI: 10.1038/s41589-018-0170-9 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.5 Å) |
Structure validation
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