6IGK

Crystal Structure of human ETB receptor in complex with Endothelin-3

6IGK の概要

• エントリーDOI: 10.2210/pdb6igk/pdb
• 分子名称: Endothelin receptor type B,Endolysin,Endothelin receptor type B, Endothelin-3, (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, ... (5 entities in total)
• 機能のキーワード: alpha helical, signaling protein-protein binding complex, signaling protein/protein binding
• 由来する生物種: Homo sapiens (Human); 詳細
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 63077.43

構造登録者

Shihoya, W.,Izume, T.,Inoue, A.,Yamashita, K.,Kadji, F.M.N.,Hirata, K.,Aoki, J.,Nishizawa, T.,Nureki, O. (登録日: 2018-09-25, 公開日: 2018-11-21, 最終更新日: 2023-11-22)

• 主引用文献: Shihoya, W.,Izume, T.,Inoue, A.,Yamashita, K.,Kadji, F.M.N.,Hirata, K.,Aoki, J.,Nishizawa, T.,Nureki, O.; Crystal structures of human ETBreceptor provide mechanistic insight into receptor activation and partial activation.; Nat Commun, 9:4711-4711, 2018; PubMed: 30413709; DOI: 10.1038/s41467-018-07094-0

実験手法

X-RAY DIFFRACTION (2 Å)