6ICG

Grb2 SH2 domain in phosphopeptide free form

Summary for 6ICG

• Entry DOI: 10.2210/pdb6icg/pdb
• Descriptor: Growth factor receptor-bound protein 2, SULFATE ION, GLYCEROL, ... (4 entities in total)
• Functional Keywords: src homology 2 domain, phosphorylated tyrosine, adapter protein, signaling protein
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 2
• Total formula weight: 22569.22

Authors

Hosoe, Y.,Numoto, N.,Inaba, S.,Ogawa, S.,Morii, H.,Abe, R.,Ito, N.,Oda, M. (deposition date: 2018-09-06, release date: 2019-07-17, Last modification date: 2023-11-22)

• Primary citation: Hosoe, Y.,Numoto, N.,Inaba, S.,Ogawa, S.,Morii, H.,Abe, R.,Ito, N.,Oda, M.; Structural and functional properties of Grb2 SH2 dimer in CD28 binding.; Biophys Physicobio., 16:80-88, 2019; PubMed: 30923665; DOI: 10.2142/biophysico.16.0_80

Experimental method

X-RAY DIFFRACTION (1.15 Å)