6IBF

Crystal structure of human phosphodiesterase 4D2 catalytic domain with inhibitor NPD-417

Summary for 6IBF

• Entry DOI: 10.2210/pdb6ibf/pdb
• Related: 6FRD 6FT0 6FTA 6IAG
• Descriptor: cAMP-specific 3',5'-cyclic phosphodiesterase 4D, ZINC ION, MAGNESIUM ION, ... (8 entities in total)
• Functional Keywords: phosphodiesterase, hydrolase, camp hydrolysis, alternative splicing
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 4
• Total formula weight: 173706.71

Authors

Singh, A.K.,Brown, D.G. (deposition date: 2018-11-29, release date: 2019-12-18)

• Primary citation: Singh, A.K.,Brown, D.G.; hPDE4D2 structure with inhibitor NPD-417; To be published,

Experimental method

X-RAY DIFFRACTION (2.31 Å)