6I3D
Crystal structure of Human soluble catechol O-methyltransferase in complex with 3,5-dinitrocatechol and Sinefungin
Summary for 6I3D
Entry DOI | 10.2210/pdb6i3d/pdb |
Descriptor | Catechol O-methyltransferase, 3,5-DINITROCATECHOL, MAGNESIUM ION, ... (5 entities in total) |
Functional Keywords | enzyme, s-adenosyl-l-methionine, catechol o-methyltransferase, transferase |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 2 |
Total formula weight | 53152.83 |
Authors | Levy, C.W. (deposition date: 2018-11-05, release date: 2019-09-18, Last modification date: 2024-05-01) |
Primary citation | Czarnota, S.,Johannissen, L.O.,Baxter, N.J.,Rummel, F.,Wilson, A.L.,Cliff, M.J.,Levy, C.W.,Scrutton, N.S.,Waltho, J.P.,Hay, S. Equatorial Active Site Compaction and Electrostatic Reorganization in Catechol-O-methyltransferase. Acs Catalysis, 9:4394-4401, 2019 Cited by PubMed: 31080692DOI: 10.1021/acscatal.9b00174 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.45 Å) |
Structure validation
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