6I2Y

Human STK10 bound to Foretinib

6I2Y の概要

• エントリーDOI: 10.2210/pdb6i2y/pdb
• 分子名称: Serine/threonine-protein kinase 10, N-(3-fluoro-4-{[6-methoxy-7-(3-morpholin-4-ylpropoxy)quinolin-4-yl]oxy}phenyl)-N'-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide (2 entities in total)
• 機能のキーワード: kinase, inhibitor, complex, lok, transferase, foretinib
• 由来する生物種: Homo sapiens (Human)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 69746.32

構造登録者

Sorrell, F.J.,Berger, B.-T.,Oerum, S.,von Delft, F.,Bountra, C.,Arrowsmith, C.,Edwards, A.M.,Knapp, S.,Elkins, J.M. (登録日: 2018-11-02, 公開日: 2018-12-12)

• 主引用文献: Sorrell, F.J.,Elkins, J.M.; Human STK10 bound to GW683134; To Be Published,

実験手法

X-RAY DIFFRACTION (2.56 Å)