6I2P
Crystal structure of the Mycobacterium tuberculosis PknB kinase domain (L33E mutant) in complex with its substrate GarA
Summary for 6I2P
Entry DOI | 10.2210/pdb6i2p/pdb |
Descriptor | Serine/threonine-protein kinase PknB, Glycogen accumulation regulator GarA, UNK-UNK-UNK-UNK-UNK, ... (7 entities in total) |
Functional Keywords | kinase, fha-domain protein, signaling protein |
Biological source | Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) More |
Total number of polymer chains | 5 |
Total formula weight | 97476.74 |
Authors | Andre-Leroux, G.,Hindie, V.,Barilone, N.,Bellinzoni, M.,Alzari, P.M. (deposition date: 2018-11-01, release date: 2019-05-22, Last modification date: 2024-01-24) |
Primary citation | Wagner, T.,Andre-Leroux, G.,Hindie, V.,Barilone, N.,Lisa, M.N.,Hoos, S.,Raynal, B.,Vulliez-Le Normand, B.,O'Hare, H.M.,Bellinzoni, M.,Alzari, P.M. Structural insights into the functional versatility of an FHA domain protein in mycobacterial signaling. Sci.Signal., 12:-, 2019 Cited by PubMed: 31064884DOI: 10.1126/scisignal.aav9504 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.37 Å) |
Structure validation
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