6I2K

Structure of EV71 complexed with its receptor SCARB2

6I2K の概要

• エントリーDOI: 10.2210/pdb6i2k/pdb
• EMDBエントリー: 0332
• 分子名称: Polyprotein, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 1-(2-aminopyridin-4-yl)-3-[(3S)-5-{4-[(E)-(ethoxyimino)methyl]phenoxy}-3-methylpentyl]imidazolidin-2-one, ... (12 entities in total)
• 機能のキーワード: enterovirus 71, scarb2, hand-foot-mouth disease, ev71 receptor, virus
• 由来する生物種: Homo sapiens (Human); 詳細
• タンパク質・核酸の鎖数: 5
• 化学式量合計: 147035.46

構造登録者

Zhou, D.,Zhao, Y.,Kotecha, A.,Fry, E.E.,Kelly, J.,Wang, X.,Rao, Z.,Rowlands, D.J.,Ren, J.,Stuart, D.I. (登録日: 2018-11-01, 公開日: 2018-11-28, 最終更新日: 2020-07-29)

• 主引用文献: Zhou, D.,Zhao, Y.,Kotecha, A.,Fry, E.E.,Kelly, J.T.,Wang, X.,Rao, Z.,Rowlands, D.J.,Ren, J.,Stuart, D.I.; Unexpected mode of engagement between enterovirus 71 and its receptor SCARB2.; Nat Microbiol, 4:414-419, 2019; PubMed: 30531980; DOI: 10.1038/s41564-018-0319-z

実験手法

ELECTRON MICROSCOPY (3.4 Å)