6I1D
Structure of the Ysh1-Mpe1 nuclease complex from S.cerevisiae
Summary for 6I1D
Entry DOI | 10.2210/pdb6i1d/pdb |
Descriptor | Endoribonuclease YSH1, Protein MPE1, ZINC ION, ... (5 entities in total) |
Functional Keywords | pre-mrna, mrna, nuclease, endonuclease, cleavage, polyadenylation, polya, cpf, metallo-beta-lactamase, 3' ends, gene regulation |
Biological source | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) More |
Total number of polymer chains | 2 |
Total formula weight | 71756.75 |
Authors | Hill, C.H.,Boreikaite, V.,Kumar, A.,Casanal, A.,Kubik, P.,Degliesposti, G.,Maslen, S.,Mariani, A.,von Loeffelholz, O.,Girbig, M.,Skehel, M.,Passmore, L.A. (deposition date: 2018-10-28, release date: 2019-02-13, Last modification date: 2024-01-24) |
Primary citation | Hill, C.H.,Boreikaite, V.,Kumar, A.,Casanal, A.,Kubik, P.,Degliesposti, G.,Maslen, S.,Mariani, A.,von Loeffelholz, O.,Girbig, M.,Skehel, M.,Passmore, L.A. Activation of the Endonuclease that Defines mRNA 3' Ends Requires Incorporation into an 8-Subunit Core Cleavage and Polyadenylation Factor Complex. Mol.Cell, 73:1217-1231.e11, 2019 Cited by PubMed: 30737185DOI: 10.1016/j.molcel.2018.12.023 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.28 Å) |
Structure validation
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