6HZY
Crystal structure of a bacterial fucosidase with inhibitor FucPUG
Summary for 6HZY
Entry DOI | 10.2210/pdb6hzy/pdb |
Descriptor | Alpha-L-fucosidase, 1,2-ETHANEDIOL, [(~{Z})-[(3~{S},4~{R},5~{S},6~{S})-6-methyl-3,4,5-tris(oxidanyl)oxan-2-ylidene]amino] ~{N}-phenylcarbamate, ... (5 entities in total) |
Functional Keywords | hydrolase |
Biological source | Bacteroides thetaiotaomicron VPI-5482 |
Total number of polymer chains | 2 |
Total formula weight | 111980.14 |
Authors | Wu, L.,Davies, G.J.,Stubbs, K.A.,Coyle, T.,Debowski, A.W. (deposition date: 2018-10-24, release date: 2019-02-20, Last modification date: 2024-01-24) |
Primary citation | Coyle, T.,Wu, L.,Debowski, A.W.,Davies, G.J.,Stubbs, K.A. Synthetic and Crystallographic Insight into Exploiting sp2Hybridization in the Development of alpha-l-Fucosidase Inhibitors. Chembiochem, 20:1365-1368, 2019 Cited by PubMed: 30663832DOI: 10.1002/cbic.201800710 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.7 Å) |
Structure validation
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