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6HVK

Pepducin UT-Pep2 a biased allosteric agonist of Urotensin-II receptor

Replaces:  6Q8L
Summary for 6HVK
Entry DOI10.2210/pdb6hvk/pdb
NMR InformationBMRB: 34320
DescriptorUrotensin-2 receptor (1 entity in total)
Functional Keywordsg protein-coupled receptor, pepducin, lipidated peptide, urotensin ii receptor, allosteric modulators, cellular signaling., peptide binding protein
Biological sourceHomo sapiens (Human)
Total number of polymer chains1
Total formula weight1456.69
Authors
Carotenuto, A.,Hoang, T.A.,Nassour, H.,Martin, R.D.,Billard, E.,Myriam, L.,Novellino, E.,Tanny, J.C.,Fournier, A.,Hebert, T.E.,Chatenet, D. (deposition date: 2018-10-11, release date: 2019-10-30, Last modification date: 2023-06-14)
Primary citationNassour, H.,Hoang, T.A.,Martin, R.D.,Dallagnol, J.C.C.,Billard, E.,Letourneau, M.,Novellino, E.,Carotenuto, A.,Allen, B.G.,Tanny, J.C.,Fournier, A.,Hebert, T.E.,Chatenet, D.
Lipidated peptides derived from intracellular loops 2 and 3 of the urotensin II receptor act as biased allosteric ligands.
J.Biol.Chem., 297:101057-101057, 2021
Cited by
PubMed: 34389356
DOI: 10.1016/j.jbc.2021.101057
PDB entries with the same primary citation
Experimental method
SOLUTION NMR
Structure validation

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