6HSV
Engineered higher-order assembly of Cholera Toxin B subunits via the addition of C-terminal parallel coiled-coiled domains
Summary for 6HSV
Entry DOI | 10.2210/pdb6hsv/pdb |
Descriptor | Toxin B subunit, PHOSPHATE ION, (4S)-2-METHYL-2,4-PENTANEDIOL, ... (5 entities in total) |
Functional Keywords | cholera toxin b, ctb, parallel coiled coils, higher order assembly, self assembly, designed protein, nanotube, toxin |
Biological source | Vibrio cholerae |
Total number of polymer chains | 20 |
Total formula weight | 281394.02 |
Authors | Pearson, A.R.,Turnbull, W.B.,Ross, J.F.,Trinh, C.H.,Webb, M.E. (deposition date: 2018-10-01, release date: 2019-03-20, Last modification date: 2024-01-24) |
Primary citation | Ross, J.F.,Wildsmith, G.C.,Johnson, M.,Hurdiss, D.L.,Hollingsworth, K.,Thompson, R.F.,Mosayebi, M.,Trinh, C.H.,Paci, E.,Pearson, A.R.,Webb, M.E.,Turnbull, W.B. Directed Assembly of Homopentameric Cholera Toxin B-Subunit Proteins into Higher-Order Structures Using Coiled-Coil Appendages. J.Am.Chem.Soc., 141:5211-5219, 2019 Cited by PubMed: 30856321DOI: 10.1021/jacs.8b11480 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.45 Å) |
Structure validation
Download full validation report