6HR7
HMG-CoA reductase from Methanothermococcus thermolithotrophicus apo form at 2.4 A resolution
Summary for 6HR7
| Entry DOI | 10.2210/pdb6hr7/pdb |
| Descriptor | HMG-CoA reductase, SULFATE ION, 2,3-DIHYDROXY-1,4-DITHIOBUTANE, ... (8 entities in total) |
| Functional Keywords | hmg-coa, mevalonate biosynthesis, statins, cholesterol biosynthesis, isoprenoids, structural rearrangement., oxidoreductase |
| Biological source | Methanothermococcus thermolithotrophicus DSM 2095 |
| Total number of polymer chains | 2 |
| Total formula weight | 94677.49 |
| Authors | Wagner, T.,Voegeli, B.,Erb, T.J.,Shima, S. (deposition date: 2018-09-26, release date: 2019-02-13, Last modification date: 2024-01-24) |
| Primary citation | Vogeli, B.,Shima, S.,Erb, T.J.,Wagner, T. Crystal structure of archaeal HMG-CoA reductase: insights into structural changes of the C-terminal helix of the class-I enzyme. Febs Lett., 593:543-553, 2019 Cited by PubMed: 30702149DOI: 10.1002/1873-3468.13331 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.4 Å) |
Structure validation
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