6HOP

Human protein kinase CK2 alpha in complex with curcumin degradation products

Summary for 6HOP

• Entry DOI: 10.2210/pdb6hop/pdb
• Descriptor: Casein kinase II subunit alpha, SULFATE ION, 1,2-ETHANEDIOL, ... (8 entities in total)
• Functional Keywords: kinase domain, transferase
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 1
• Total formula weight: 41220.80

Authors

Battistutta, R.,Lolli, G. (deposition date: 2018-09-18, release date: 2019-10-02, Last modification date: 2024-01-24)

• Primary citation: Cozza, G.,Zonta, F.,Dalle Vedove, A.,Venerando, A.,Dall'Acqua, S.,Battistutta, R.,Ruzzene, M.,Lolli, G.; Biochemical and cellular mechanism of protein kinase CK2 inhibition by deceptive curcumin.; Febs J., 287:1850-1864, 2020; PubMed: 31661600; DOI: 10.1111/febs.15111

Experimental method

X-RAY DIFFRACTION (1.55 Å)