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6HO8

TRANSCRIPTIONAL REPRESSOR ETHR FROM MYCOBACTERIUM TUBERCULOSIS IN COMPLEX WITH BDM44815

Summary for 6HO8
Entry DOI10.2210/pdb6ho8/pdb
DescriptorHTH-type transcriptional regulator EthR, ~{N}-[3,3,3-tris(fluoranyl)propyl]benzenesulfonamide (3 entities in total)
Functional Keywordshelix-turn-helix, dna binding protein, tetr-family, complex, inhibitor, drug design, tuberculosis, ethionamide
Biological sourceMycobacterium tuberculosis CDC1551
Total number of polymer chains1
Total formula weight25181.22
Authors
Wintjens, R.,Wohlkonig, A. (deposition date: 2018-09-17, release date: 2018-12-26, Last modification date: 2019-01-23)
Primary citationTanina, A.,Wohlkonig, A.,Soror, S.H.,Flipo, M.,Villemagne, B.,Prevet, H.,Deprez, B.,Moune, M.,Peree, H.,Meyer, F.,Baulard, A.R.,Willand, N.,Wintjens, R.
A comprehensive analysis of the protein-ligand interactions in crystal structures of Mycobacterium tuberculosis EthR.
Biochim Biophys Acta Proteins Proteom, 1867:248-258, 2018
Cited by
PubMed: 30553830
DOI: 10.1016/j.bbapap.2018.12.003
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.98 Å)
Structure validation

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