Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

6HMB

STRUCTURE OF PROTEIN KINASE CK2 CATALYTIC SUBUNIT (ISOFORM CK2ALPHA'; CSNK2A2 Gene product) IN COMPLEX WITH the inhibitor CX-4945 (Silmitasertib)

Summary for 6HMB
Entry DOI10.2210/pdb6hmb/pdb
Related6HMC 6HMD 6HMQ
DescriptorCasein kinase II subunit alpha', 1,2-ETHANEDIOL, CHLORIDE ION, ... (5 entities in total)
Functional Keywordsprotein kinase ck2, casein kinase 2, catalytic subunit ck2alpha', csnk2a2, transferase
Biological sourceHomo sapiens (Human)
Total number of polymer chains1
Total formula weight43921.22
Authors
Niefind, K.,Lindenblatt, D.,Applegate, V.M.,Jose, J.,Le Borgne, M. (deposition date: 2018-09-12, release date: 2019-03-27, Last modification date: 2019-10-09)
Primary citationLindenblatt, D.,Nickelsen, A.,Applegate, V.M.,Hochscherf, J.,Witulski, B.,Bouaziz, Z.,Marminon, C.,Bretner, M.,Le Borgne, M.,Jose, J.,Niefind, K.
Diacritic Binding of an Indenoindole Inhibitor by CK2 alpha Paralogs Explored by a Reliable Path to Atomic Resolution CK2 alpha ' Structures.
Acs Omega, 4:5471-5478, 2019
Cited by
PubMed: 31559376
DOI: 10.1021/acsomega.8b03415
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.04 Å)
Structure validation

217705

PDB entries from 2024-03-27

PDB statisticsPDBj update infoContact PDBjnumon