6HKS
Crystal structure of the PTPN3 PDZ domain bound to the HPV16 E6 oncoprotein C-terminal peptide
Summary for 6HKS
Entry DOI | 10.2210/pdb6hks/pdb |
Descriptor | Tyrosine-protein phosphatase non-receptor type 3, Protein E6, IODIDE ION, ... (4 entities in total) |
Functional Keywords | pdz domain protein tyrosine phosphatase human papillomavirus e6 oncoprotein pdz binding motif, hydrolase |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 12 |
Total formula weight | 85378.20 |
Authors | Genera, M.,Haouz, A.,Caillet-Saguy, C. (deposition date: 2018-09-07, release date: 2019-05-22, Last modification date: 2024-01-17) |
Primary citation | Genera, M.,Samson, D.,Raynal, B.,Haouz, A.,Baron, B.,Simenel, C.,Guerois, R.,Wolff, N.,Caillet-Saguy, C. Structural and functional characterization of the PDZ domain of the human phosphatase PTPN3 and its interaction with the human papillomavirus E6 oncoprotein. Sci Rep, 9:7438-7438, 2019 Cited by PubMed: 31092861DOI: 10.1038/s41598-019-43932-x PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.19441072073 Å) |
Structure validation
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