6HKP

Factor Inhibiting HIF (FIH) in complex with zinc, NOG and ASPP2 (970-992)

6HKP の概要

• エントリーDOI: 10.2210/pdb6hkp/pdb
• 分子名称: Hypoxia-inducible factor 1-alpha inhibitor, Apoptosis-stimulating of p53 protein 2, SULFATE ION, ... (7 entities in total)
• 機能のキーワード: non-heme, dioxygenase, oxygenase, metal-binding, transcription, double stranded beta-helix, dsbh, facial triad, asparaginyl/aspartyl hydroxylase, epigenetic regulation, signaling, ard, beta-hydroxylation, activator-inhibitor, oxidoreductase-peptide complex, oxidoreductase, ankyrin repeat domain, apoptosis, p53 binding protein, ank repeat, sh3 domain, ankyrin repeats, gene regulation
• 由来する生物種: Homo sapiens (Human); 詳細
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 44084.34

構造登録者

Leissing, T.M.,Clifton, I.J.,Lu, X.,Schofield, C.J. (登録日: 2018-09-07, 公開日: 2019-09-18, 最終更新日: 2024-01-17)

• 主引用文献: Leissing, T.M.,Clifton, I.J.,Lu, X.,Schofield, C.J.; Factor Inhibiting HIF (FIH) in complex with zinc, NOG and ASPP2 (970-992); To Be Published,

実験手法

X-RAY DIFFRACTION (1.9 Å)