6HK1

Crystal structure of the Thiazole synthase from Methanothermococcus thermolithotrophicus co-crystallized with Tb-Xo4

Summary for 6HK1

Entry DOI	10.2210/pdb6hk1/pdb
Descriptor	Thiazole synthase, TERBIUM(III) ION, [[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl] [(2R,3R)-2,3,5-tris(oxidanyl)-4-oxidanylidene-pentyl] hydrogen phosphate, ... (8 entities in total)
Functional Keywords	native purification, de novo phasing, nucleating agent, crystallophore, tb-xo4, lanthanide complex, molecular glue, biosynthetic protein
Biological source	Methanothermococcus thermolithotrophicus
Total number of polymer chains	6
Total formula weight	179440.29
Authors	Engilberge, S.,Wagner, T.,Santoni, G.,Breyton, C.,Shima, S.,Franzetti, B.,Riobe, F.,Maury, O.,Girard, E. (deposition date: 2018-09-05, release date: 2019-06-19, Last modification date: 2019-08-21)
Primary citation	Engilberge, S.,Wagner, T.,Santoni, G.,Breyton, C.,Shima, S.,Franzetti, B.,Riobe, F.,Maury, O.,Girard, E. Protein crystal structure determination with the crystallophore, a nucleating and phasing agent. J.Appl.Crystallogr., 52:722-731, 2019 Cited by PubMed: 31396026 DOI: 10.1107/S1600576719006381 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.55 Å)

Structure validation