6HGV
Soluble epoxide hydrolase in complex with talinolol
Summary for 6HGV
Entry DOI | 10.2210/pdb6hgv/pdb |
Descriptor | Bifunctional epoxide hydrolase 2, MAGNESIUM ION, R-Talinolol, ... (4 entities in total) |
Functional Keywords | inhibitor, complex, seh, hydrolase |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 1 |
Total formula weight | 40036.33 |
Authors | Kramer, J.S.,Pogoryelov, D.,Hiesinger, K.,Proschak, E. (deposition date: 2018-08-23, release date: 2019-07-03, Last modification date: 2024-01-17) |
Primary citation | Hiesinger, K.,Kramer, J.S.,Achenbach, J.,Moser, D.,Weber, J.,Wittmann, S.K.,Morisseau, C.,Angioni, C.,Geisslinger, G.,Kahnt, A.S.,Kaiser, A.,Proschak, A.,Steinhilber, D.,Pogoryelov, D.,Wagner, K.,Hammock, B.D.,Proschak, E. Computer-Aided Selective Optimization of Side Activities of Talinolol. Acs Med.Chem.Lett., 10:899-903, 2019 Cited by PubMed: 31223445DOI: 10.1021/acsmedchemlett.9b00075 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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