6HG8

Crystal structure of the R460G disease-causing mutant of the human dihydrolipoamide dehydrogenase.

Summary for 6HG8

• Entry DOI: 10.2210/pdb6hg8/pdb
• Related: 5J5Z 5NHG
• Descriptor: Dihydrolipoyl dehydrogenase, mitochondrial, FLAVIN-ADENINE DINUCLEOTIDE, SULFATE ION, ... (5 entities in total)
• Functional Keywords: oxidoreductase, lipoamide dehydrogenase (e3) component, disease-causing mutant, e3 deficiency
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 2
• Total formula weight: 107823.99

Authors

Ambrus, A.,Szabo, E.,Weichsel, A.,Bui, D.,Wilk, P.,Torocsik, B.,Weiss, M.S.,Montfort, W.R.,Jordan, F.,Adam-Vizi, V. (deposition date: 2018-08-22, release date: 2019-09-04, Last modification date: 2024-11-20)

• Primary citation: Ambrus, A.,Szabo, E.,Weichsel, A.,Bui, D.,Torocsik, B.,Montfort, W.R.,Jordan, F.,Adam-Vizi, V.; Crystal structure of the R460G disease-causing mutant of the human dihydrolipoamide dehydrogenase.; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.76 Å)