6HG5

Influenza A virus N6 neuraminidase complex with Oseltamivir (Duck/England/56).

Summary for 6HG5

• Entry DOI: 10.2210/pdb6hg5/pdb
• Descriptor: Neuraminidase, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (10 entities in total)
• Functional Keywords: influenza, a, oseltamivir, n6, neuraminidase, duck, virus, enzyme, inhibitor, complex, hydrolase, gs4071, tamiflu
• Biological source: Influenza A virus (strain A/Duck/England/1/1956 H11N6)
• Total number of polymer chains: 4
• Total formula weight: 181194.06

Authors

Salinger, M.T.,Hobbs, J.R.,Murray, J.W.,Laver, W.G.,Kuhn, P.,Garman, E.F. (deposition date: 2018-08-22, release date: 2018-08-29, Last modification date: 2024-11-13)

• Primary citation: Salinger, M.T.,Hobbs, J.R.,Murray, J.W.,Laver, W.G.,Kuhn, P.,Garman, E.F.; High Resolution Structures of Viral Neuraminidase with Drugs Bound in the Active Site.; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.6 Å)