6HG5

Influenza A virus N6 neuraminidase complex with Oseltamivir (Duck/England/56).

6HG5 の概要

• エントリーDOI: 10.2210/pdb6hg5/pdb
• 分子名称: Neuraminidase, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (10 entities in total)
• 機能のキーワード: influenza, a, oseltamivir, n6, neuraminidase, duck, virus, enzyme, inhibitor, complex, hydrolase, gs4071, tamiflu
• 由来する生物種: Influenza A virus (strain A/Duck/England/1/1956 H11N6)
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 181194.06

構造登録者

Salinger, M.T.,Hobbs, J.R.,Murray, J.W.,Laver, W.G.,Kuhn, P.,Garman, E.F. (登録日: 2018-08-22, 公開日: 2018-08-29, 最終更新日: 2024-01-17)

• 主引用文献: Salinger, M.T.,Hobbs, J.R.,Murray, J.W.,Laver, W.G.,Kuhn, P.,Garman, E.F.; High Resolution Structures of Viral Neuraminidase with Drugs Bound in the Active Site.; To Be Published,

実験手法

X-RAY DIFFRACTION (1.6 Å)