6HG3
Hybrid dihydroorotase domain of human CAD with E. coli flexible loop, bound to dihydroorotate
Summary for 6HG3
| Entry DOI | 10.2210/pdb6hg3/pdb |
| Descriptor | CAD protein, FORMIC ACID, ZINC ION, ... (5 entities in total) |
| Functional Keywords | de novo pyrimidine biosynthesis, cad, tim-barrel, carboxylated lysine, biosynthetic protein |
| Biological source | Homo sapiens (Human) |
| Total number of polymer chains | 1 |
| Total formula weight | 40756.09 |
| Authors | Ramon-Maiques, S.,Del Cano-Ochoa, F. (deposition date: 2018-08-22, release date: 2018-10-24, Last modification date: 2024-01-17) |
| Primary citation | Del Cano-Ochoa, F.,Grande-Garcia, A.,Reverte-Lopez, M.,D'Abramo, M.,Ramon-Maiques, S. Characterization of the catalytic flexible loop in the dihydroorotase domain of the human multi-enzymatic protein CAD. J. Biol. Chem., 293:18903-18913, 2018 Cited by PubMed: 30315107DOI: 10.1074/jbc.RA118.005494 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.97 Å) |
Structure validation
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