6HCX

Influenza Virus N9 Neuraminidase A complex with Zanamivir molecule (Tern).

Summary for 6HCX

DescriptorNeuraminidase, N-ACETYL-D-GLUCOSAMINE, BETA-D-MANNOSE, ... (9 entities in total)
Functional Keywordscomplex, zanamivir, relenza, neuraminidase, n9, influenza, virus, hydrolase, enzyme, inhibitor
Biological sourceInfluenza A virus (strain A/Tern/Australia/G70C/1975 H11N9)
Total number of polymer chains1
Total molecular weight47039.96
Authors
Salinger, M.T.,Hobbs, J.R.,Murray, J.W.,Laver, W.G.,Kuhn, P.,Garman, E.F. (deposition date: 2018-08-16, release date: 2018-08-29, Last modification date: 2018-09-05)
Primary citation
Salinger, M.T.,Hobbs, J.R.,Murray, J.W.,Laver, W.G.,Kuhn, P.,Garman, E.F.
High Resolution Structures of Viral Neuraminidase with Drugs Bound in the Active Site. (In preparation)
To Be Published,
Experimental method
X-RAY DIFFRACTION (1.3 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.127400.6%0.3%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution