Synthetic Self-assembling ADDomer Platform for Highly Efficient Vaccination by Genetically-encoded Multi-epitope Display

This is a large structure.

Summary for 6HCR

EMDB information0198
DescriptorPenton protein (1 entity in total)
Functional Keywordsengineered, virus, like, particle, addomer, ad3, penton, base, adenovirus, synthetic, vaccine, biobrick, human, homosapien, dodecahedron, icosohedral, epitode, display, scaffold, virus like particle
Biological sourceHuman adenovirus B serotype 3
Total number of polymer chains60
Total molecular weight3815897.58
Bufton, J.C.,Berger, I.,Schaffitzel, C.,Garzoni, F.,Rabi, F.A. (deposition date: 2018-08-16, release date: 2019-08-28, Last modification date: 2019-10-30)
Primary citation
Vragniau, C.,Bufton, J.C.,Garzoni, F.,Stermann, E.,Rabi, F.,Terrat, C.,Guidetti, M.,Josserand, V.,Williams, M.,Woods, C.J.,Viedma, G.,Bates, P.,Verrier, B.,Chaperot, L.,Schaffitzel, C.,Berger, I.,Fender, P.
Synthetic self-assembling ADDomer platform for highly efficient vaccination by genetically encoded multiepitope display.
Sci Adv, 5:eaaw2853-eaaw2853, 2019
PubMed: 31620562 (PDB entries with the same primary citation)
DOI: 10.1126/sciadv.aaw2853
MImport into Mendeley
Experimental method

Structure validation

ClashscoreRamachandran outliersSidechain outliers20 1.0%MetricValuePercentile RanksWorseBetterPercentile relative to all structuresPercentile relative to all EM structures
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