6H78
E1 enzyme for ubiquitin like protein activation.
Summary for 6H78
Entry DOI | 10.2210/pdb6h78/pdb |
Descriptor | Ubiquitin-like modifier-activating enzyme 5, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... (7 entities in total) |
Functional Keywords | ubiquitin like protein activating enzyme, transferase |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 16 |
Total formula weight | 545129.19 |
Authors | Soudah, N.,Padala, P.,Hassouna, F.,Mashahreh, B.,Lebedev, A.A.,Isupov, M.N.,Cohen-Kfir, E.,Wiener, R. (deposition date: 2018-07-30, release date: 2018-10-31, Last modification date: 2024-01-17) |
Primary citation | Soudah, N.,Padala, P.,Hassouna, F.,Kumar, M.,Mashahreh, B.,Lebedev, A.A.,Isupov, M.N.,Cohen-Kfir, E.,Wiener, R. An N-Terminal Extension to UBA5 Adenylation Domain Boosts UFM1 Activation: Isoform-Specific Differences in Ubiquitin-like Protein Activation. J.Mol.Biol., 431:463-478, 2019 Cited by PubMed: 30412706DOI: 10.1016/j.jmb.2018.10.007 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.7 Å) |
Structure validation
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