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6H4G

Regulatory subunit of a cAMP-independent protein kinase A from Trypanosoma brucei: E311A, T318R, V319A mutant bound to cAMP in the A site

Summary for 6H4G
Entry DOI10.2210/pdb6h4g/pdb
Related6FLO
DescriptorProtein kinase A regulatory subunit, ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, INOSINE, ... (4 entities in total)
Functional Keywordsprotein kinase a, regulatory subunit, nucleoside-binding protein, signaling protein
Biological sourceTrypanosoma brucei brucei (strain 927/4 GUTat10.1)
Total number of polymer chains2
Total formula weight69960.92
Authors
Volpato Santos, Y.,Lorentzen, E.,Basquin, J.,Boshart, M. (deposition date: 2018-07-21, release date: 2019-08-14, Last modification date: 2024-01-17)
Primary citationOber, V.,Githure, G.B.,Volpato Santos, Y.,Becker, S.,Moya, G.,Basquin, J.,Schwede, F.,Lorentzen, E.,Boshart, M.
Purine nucleosides replace cAMP in allosteric regulation of PKA in trypanosomatid pathogens
Elife, 2023
Cited by
DOI: 10.7554/eLife.91040.1
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.14351698698 Å)
Structure validation

217705

數據於2024-03-27公開中

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