6H2U
Crystal structure of human METTL5-TRMT112 complex, the 18S rRNA m6A1832 methyltransferase at 1.6A resolution
Summary for 6H2U
Entry DOI | 10.2210/pdb6h2u/pdb |
Descriptor | Methyltransferase-like protein 5, Multifunctional methyltransferase subunit TRM112-like protein, S-ADENOSYLMETHIONINE, ... (6 entities in total) |
Functional Keywords | rrna maturation, methyltransferase, translation, ribosome synthesis, transferase |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 2 |
Total formula weight | 38937.97 |
Authors | van Tran, N.,Graille, M. (deposition date: 2018-07-16, release date: 2019-07-31, Last modification date: 2019-09-18) |
Primary citation | van Tran, N.,Ernst, F.G.M.,Hawley, B.R.,Zorbas, C.,Ulryck, N.,Hackert, P.,Bohnsack, K.E.,Bohnsack, M.T.,Jaffrey, S.R.,Graille, M.,Lafontaine, D.L.J. The human 18S rRNA m6A methyltransferase METTL5 is stabilized by TRMT112. Nucleic Acids Res., 47:7719-7733, 2019 Cited by PubMed: 31328227DOI: 10.1093/nar/gkz619 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.6 Å) |
Structure validation
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