6H1I
Crystal structure of human Pirin in complex with bisamide compound 2
Summary for 6H1I
Entry DOI | 10.2210/pdb6h1i/pdb |
Descriptor | Pirin, FE (III) ION, GLYCEROL, ... (5 entities in total) |
Functional Keywords | transcriptional coregulator, quercetin 2, 3-dioxygenase, inhibitor, transcription |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 1 |
Total formula weight | 33227.28 |
Authors | Ali, S.,Le Bihan, Y.V.,van Montfort, R.L.M. (deposition date: 2018-07-11, release date: 2018-11-28, Last modification date: 2024-01-17) |
Primary citation | Meyers, J.,Chessum, N.E.A.,Ali, S.,Mok, N.Y.,Wilding, B.,Pasqua, A.E.,Rowlands, M.,Tucker, M.J.,Evans, L.E.,Rye, C.S.,O'Fee, L.,Le Bihan, Y.V.,Burke, R.,Carter, M.,Workman, P.,Blagg, J.,Brown, N.,van Montfort, R.L.M.,Jones, K.,Cheeseman, M.D. Privileged Structures and Polypharmacology within and between Protein Families. ACS Med Chem Lett, 9:1199-1204, 2018 Cited by PubMed: 30613326DOI: 10.1021/acsmedchemlett.8b00364 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.69 Å) |
Structure validation
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