6H05

Cryo-electron microscopic structure of the dihydrolipoamide succinyltransferase (E2) component of the human alpha-ketoglutarate (2-oxoglutarate) dehydrogenase complex [residues 218-453]

6H05 の概要

• エントリーDOI: 10.2210/pdb6h05/pdb
• EMDBエントリー: 0108
• 分子名称: Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial (1 entity in total)
• 機能のキーワード: alpha-ketoglutarate dehydrogenase complex; 2-oxoglutarate dehydrogenase complex; dihydrolipoamide succinyltransferase; e2 component, transferase
• 由来する生物種: Homo sapiens (Human)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 45543.00

構造登録者

Nagy, B.,Zambo, Z.,Hubert, A.,Polak, M.,Nemeria, N.S.,Novacek, J.,Jordan, F.,Adam-Vizi, V.,Ambrus, A. (登録日: 2018-07-06, 公開日: 2020-01-22, 最終更新日: 2024-05-15)

• 主引用文献: Nagy, B.,Polak, M.,Ozohanics, O.,Zambo, Z.,Szabo, E.,Hubert, A.,Jordan, F.,Novacek, J.,Adam-Vizi, V.,Ambrus, A.; Structure of the dihydrolipoamide succinyltransferase (E2) component of the human alpha-ketoglutarate dehydrogenase complex (hKGDHc) revealed by cryo-EM and cross-linking mass spectrometry: Implications for the overall hKGDHc structure.; Biochim Biophys Acta Gen Subj, 1865:129889-129889, 2021; PubMed: 33684457; DOI: 10.1016/j.bbagen.2021.129889

実験手法

ELECTRON MICROSCOPY (2.9 Å)