6GZ7

Polyamide - DNA complex NMR structure

Summary for 6GZ7

• Entry DOI: 10.2210/pdb6gz7/pdb
• NMR Information: BMRB: 34296
• Descriptor: DNA (5'-D(*CP*GP*AP*TP*GP*TP*AP*CP*AP*TP*CP*G)-3'), dimethyl-[3-[3-[[1-methyl-4-[[1-methyl-4-[[1-methyl-4-[[1-methyl-4-[4-[[1-methyl-4-[[1-methyl-4-[[1-methyl-4-[(1-propan-2-ylimidazol-2-yl)carbonylamino]pyrrol-2-yl]carbonylamino]pyrrol-2-yl]carbonylamino]pyrrol-2-yl]carbonylamino]butanoylamino]imidazol-2-yl]carbonylamino]pyrrol-2-yl]carbonylamino]pyrrol-2-yl]carbonylamino]pyrrol-2-yl]carbonylamino]propanoylamino]propyl]azanium (2 entities in total)
• Functional Keywords: polyamide dna complex, unknown function
• Biological source: synthetic construct
• Total number of polymer chains: 2
• Total formula weight: 9132.59

Authors

Aman, K. (deposition date: 2018-07-03, release date: 2018-11-28, Last modification date: 2021-06-23)

• Primary citation: Aman, K.,Padroni, G.,Parkinson, J.A.,Welte, T.,Burley, G.A.; Structural and Kinetic Profiling of Allosteric Modulation of Duplex DNA Induced by DNA-Binding Polyamide Analogues.; Chemistry, 25:2757-2763, 2019; PubMed: 30407668; DOI: 10.1002/chem.201805338

Experimental method

SOLUTION NMR