6GXX
Fab fragment of an antibody selective for alpha-1-antitrypsin in the native conformation
Summary for 6GXX
Entry DOI | 10.2210/pdb6gxx/pdb |
Descriptor | FAB 1D9 heavy chain, FAB 1D9 light chain, MAGNESIUM ION, ... (4 entities in total) |
Functional Keywords | antibody fragment, antitrypsin binding, diagnostic, monoclonal, protein binding, conformationally-selective |
Biological source | Mus musculus (house mouse) More |
Total number of polymer chains | 2 |
Total formula weight | 48044.64 |
Authors | Elliston, E.L.K.,Miranda, E.,Perez, J.,Lomas, D.A.,Irving, J.A. (deposition date: 2018-06-27, release date: 2019-07-10, Last modification date: 2024-01-17) |
Primary citation | Elliston, E.L.K.,Miranda, E.,Perez, J.,Irving, J.A.,Lomas, D.A. Characterisation of a monoclonal antibody conformationally-selective for native alpha-1-antitrypsin To Be Published, |
Experimental method | X-RAY DIFFRACTION (1.85 Å) |
Structure validation
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