6GX9

Crystal structure of the TNPO3 - CPSF6 RSLD complex

Summary for 6GX9

DescriptorTransportin-3, Cleavage and polyadenylation specificity factor subunit 6, MAGNESIUM ION, ... (6 entities in total)
Functional Keywordskaryopherin-cargo complex, nuclear import, sr-like domain, nuclear protein
Biological sourceHomo sapiens (Human)
Total number of polymer chains4
Total molecular weight227920.07
Authors
Cherepanov, P.,Cook, N. (deposition date: 2018-06-26, release date: 2019-03-13)
Primary citation
Jang, S.,Cook, N.,Bedwell, G.J.,Dudek, A.M.,Pye, V.E.,Singh, P.K.,Cherepanov, P.,Engelman, A.
Differential role for phosphorylation in alternative polyadenylation function versus nuclear import of SR-like protein CPSF6
To Be Published,
Experimental method
X-RAY DIFFRACTION (2.7 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.2483 0.1% 2.3% 1.6%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

Molmil generated image of 6gx9
no rotation
Molmil generated image of 6gx9
rotated about x axis by 90°
Molmil generated image of 6gx9
rotated about y axis by 90°

More Biological unit images

Molmil generated image of 6gx9
no rotation
Molmil generated image of 6gx9
rotated about x axis by 90°
Molmil generated image of 6gx9
rotated about y axis by 90°
(*)In the case of coarse surface representation, the asymmetric unit is shown as red ribbon representation.
Coordinate files for Biological unit (6gx9.pdb2.gz [151.35 KB])
Coordinate files for Biological unit (6gx9.pdb1.gz [151.95 KB])