6GWJ
Human OSGEP / LAGE3 / GON7 complex
Summary for 6GWJ
Entry DOI | 10.2210/pdb6gwj/pdb |
Descriptor | EKC/KEOPS complex subunit LAGE3, EKC/KEOPS complex subunit GON7, Probable tRNA N6-adenosine threonylcarbamoyltransferase, ... (8 entities in total) |
Functional Keywords | trna, t6a modification, rna binding protein |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 3 |
Total formula weight | 63915.47 |
Authors | Missoury, S.,Liger, D.,Durand, D.,Collinet, B.,Tilbeurgh, V.H. (deposition date: 2018-06-25, release date: 2019-07-03, Last modification date: 2024-05-15) |
Primary citation | Arrondel, C.,Missoury, S.,Snoek, R.,Patat, J.,Menara, G.,Collinet, B.,Liger, D.,Durand, D.,Gribouval, O.,Boyer, O.,Buscara, L.,Martin, G.,Machuca, E.,Nevo, F.,Lescop, E.,Braun, D.A.,Boschat, A.C.,Sanquer, S.,Guerrera, I.C.,Revy, P.,Parisot, M.,Masson, C.,Boddaert, N.,Charbit, M.,Decramer, S.,Novo, R.,Macher, M.A.,Ranchin, B.,Bacchetta, J.,Laurent, A.,Collardeau-Frachon, S.,van Eerde, A.M.,Hildebrandt, F.,Magen, D.,Antignac, C.,van Tilbeurgh, H.,Mollet, G. Defects in t 6 A tRNA modification due to GON7 and YRDC mutations lead to Galloway-Mowat syndrome. Nat Commun, 10:3967-3967, 2019 Cited by PubMed: 31481669DOI: 10.1038/s41467-019-11951-x PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.95 Å) |
Structure validation
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