Crystal structure of a FimH*DsG complex from E.coli F18 with bound dimannoside Man(alpha1-3)Man in space group P213

Summary for 6GU0

DescriptorFimH protein, FimG protein, ALPHA-D-MANNOSE, ... (6 entities in total)
Functional Keywordstype i pilus, catch-bond, cell adhesion, lectin, upec, infection, mannose
Biological sourceEscherichia coli F18+
Total number of polymer chains2
Total molecular weight30940.32
Primary citation
Sauer, M.M.,Jakob, R.P.,Luber, T.,Canonica, F.,Navarra, G.,Ernst, B.,Unverzagt, C.,Maier, T.,Glockshuber, R.
Binding of the bacterial adhesin FimH to its natural, multivalent high-mannose type glycan targets.
J. Am. Chem. Soc., 2018
PubMed: 30543411 (PDB entries with the same primary citation)
DOI: 10.1021/jacs.8b10736
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.19200 0.4% 0.3%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

Molmil generated image of 6gu0
no rotation
Molmil generated image of 6gu0
rotated about x axis by 90°
Molmil generated image of 6gu0
rotated about y axis by 90°
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