6GTZ

Crystal structure of a FimH*DsG complex from E.coli F18 with bound dimannoside Man(alpha1-3)Man in space group P21

Summary for 6GTZ

DescriptorFimH protein, FimG protein, ALPHA-D-MANNOSE, ... (5 entities in total)
Functional Keywordstype i pilus, catch-bond, cell adhesion, lectin, upec, infection, mannose
Biological sourceEscherichia coli F18+
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Total number of polymer chains4
Total molecular weight61688.52
Authors
Primary citation
Sauer, M.M.,Jakob, R.P.,Luber, T.,Canonica, F.,Navarra, G.,Ernst, B.,Unverzagt, C.,Maier, T.,Glockshuber, R.
Binding of the bacterial adhesin FimH to its natural, multivalent high-mannose type glycan targets.
J. Am. Chem. Soc., 2018
PubMed: 30543411 (PDB entries with the same primary citation)
DOI: 10.1021/jacs.8b10736
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (1.719 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.203100 0.3%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

Molmil generated image of 6gtz
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Molmil generated image of 6gtz
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Molmil generated image of 6gtz
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More Biological unit images

Molmil generated image of 6gtz
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Molmil generated image of 6gtz
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Molmil generated image of 6gtz
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(*)In the case of coarse surface representation, the asymmetric unit is shown as red ribbon representation.
Coordinate files for Biological unit (6gtz.pdb1.gz [141.17 KB])
Coordinate files for Biological unit (6gtz.pdb2.gz [141.74 KB])
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