6GTY
Crystal structure of the FimH lectin domain from E.coli K12 in complex with the dimannoside Man(alpha1-6)Man
Summary for 6GTY
Entry DOI | 10.2210/pdb6gty/pdb |
Descriptor | Type 1 fimbrin D-mannose specific adhesin, alpha-D-mannopyranose-(1-6)-methyl alpha-D-mannopyranoside (3 entities in total) |
Functional Keywords | type i pilus, catch-bond, cell adhesion, lectin, upec, infection, mannose |
Biological source | Escherichia coli K-12 |
Total number of polymer chains | 5 |
Total formula weight | 86365.76 |
Authors | Jakob, R.P.,Sauer, M.M.,Luber, T.,Canonica, F.,Navarra, G.,Ernst, B.,Unverzagt, C.,Maier, T.,Glockshuber, R. (deposition date: 2018-06-19, release date: 2019-01-16, Last modification date: 2024-01-17) |
Primary citation | Sauer, M.M.,Jakob, R.P.,Luber, T.,Canonica, F.,Navarra, G.,Ernst, B.,Unverzagt, C.,Maier, T.,Glockshuber, R. Binding of the Bacterial Adhesin FimH to Its Natural, Multivalent High-Mannose Type Glycan Targets. J.Am.Chem.Soc., 141:936-944, 2019 Cited by PubMed: 30543411DOI: 10.1021/jacs.8b10736 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.9 Å) |
Structure validation
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